Question 1

Where is Hotel Serio?

Accepted Answer

Hotel Serio is in Shinjuku, Tokyo, Japan. You can see its exact position from the map coordinates and the Street View link.

Question 2

Which scene of Weathering With You does Hotel Serio appear in?

Accepted Answer

Hotel Serio is a real place that appears in Weathering With You.

Question 3

Can I visit Hotel Serio?

Accepted Answer

Yes. Hotel Serio is a real place you can visit. Check what it looks like on Street View before you go.

Question 4

Where was Weathering With You filmed?

Accepted Answer

Anime and manga are not filmed the way live action is. Their backgrounds are painted from photographs of real locations, and Hotel Serio is one of those real places.